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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDH5 All Species: 15.45
Human Site: Y685 Identified Species: 42.5
UniProt: P33151 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P33151 NP_001786.2 784 87516 Y685 L D A R P S L Y A Q V Q K P P
Chimpanzee Pan troglodytes XP_523383 869 96866 Y770 L D A R P S L Y A Q V Q K P P
Rhesus Macaque Macaca mulatta XP_001082385 785 87425 Y686 L D A R P S L Y A Q V Q K P P
Dog Lupus familis XP_546894 772 86269 M693 V H A G P G E M A A M I E A K
Cat Felis silvestris
Mouse Mus musculus P55284 784 87884 Y685 M D A R P A V Y T Q V Q K P P
Rat Rattus norvegicus P55280 789 88322 S716 T D V R D F I S Q R L R K M N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q8QGH3 798 89138 E703 Q D M L P E I E S L S R Y V P
Frog Xenopus laevis Q91838 790 88487 E696 Q D M K P E I E S L S R Y V T
Zebra Danio Brachydanio rerio NP_571289 800 88914 Q705 K D M K P E L Q Y G M R P G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90 98.2 79.3 N.A. 75.5 40.1 N.A. N.A. 41.5 38.4 40.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 90 98.8 88.7 N.A. 85.9 58.5 N.A. N.A. 58.5 56.9 57.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 20 N.A. 73.3 20 N.A. N.A. 20 13.3 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 40 N.A. 93.3 46.6 N.A. N.A. 40 40 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 56 0 0 12 0 0 45 12 0 0 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 89 0 0 12 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 34 12 23 0 0 0 0 12 0 0 % E
% Phe: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 12 0 12 0 0 0 12 0 0 0 12 0 % G
% His: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 34 0 0 0 0 12 0 0 0 % I
% Lys: 12 0 0 23 0 0 0 0 0 0 0 0 56 0 12 % K
% Leu: 34 0 0 12 0 0 45 0 0 23 12 0 0 0 12 % L
% Met: 12 0 34 0 0 0 0 12 0 0 23 0 0 12 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % N
% Pro: 0 0 0 0 89 0 0 0 0 0 0 0 12 45 56 % P
% Gln: 23 0 0 0 0 0 0 12 12 45 0 45 0 0 0 % Q
% Arg: 0 0 0 56 0 0 0 0 0 12 0 45 0 0 0 % R
% Ser: 0 0 0 0 0 34 0 12 23 0 23 0 0 0 0 % S
% Thr: 12 0 0 0 0 0 0 0 12 0 0 0 0 0 12 % T
% Val: 12 0 12 0 0 0 12 0 0 0 45 0 0 23 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 45 12 0 0 0 23 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _